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Paul E. Sax, MD
Infectious Diseases Physician · Professor of Medicine · HIV Specialist
Paul E. Sax, MD, is Clinical Director of the Division of Infectious Diseases at Brigham and Women’s Hospital and Professor of Medicine at Harvard Medical School. He is internationally recognized for HIV clinical care, infectious-disease education, clinical research and clear communication of complex medical evidence.
About Dr. Sax
His career combines infectious-disease clinical leadership, HIV medicine,
medical education, editorial work and research involving antiretroviral therapy.
Clinical and academic leadership
Dr. Sax serves as Clinical Director of the Division of Infectious Diseases at
Brigham and Women’s Hospital, holds the Bruce A. Beal and Robert L. Beal
Distinguished Chair in Infectious Diseases and is Professor of Medicine at Harvard Medical School.
Editorial and educational contribution
He is Editor-in-Chief of Clinical Infectious Diseases, a Section Editor for
the HIV/AIDS section of UpToDate and a long-standing writer and educator
on HIV, antibiotics, emerging infections and clinical practice.
Areas of expertise
ClearMed Journal presents medicines by their generic ingredient names and separates
antibiotics, antiparasitic medicines and antiviral therapies accurately.
Infectious diseases
Clinical evaluation, treatment decisions, prevention and communication across a broad range of infections.
HIV medicine
Antiretroviral therapy, treatment safety, drug toxicity, prevention and long-term HIV care.
Azithromycin
Educational context for azithromycin, a macrolide antibacterial medicine used for selected susceptible bacterial infections.
Antibiotic stewardship
Selecting antibiotics only when clinically indicated, limiting unnecessary exposure and reducing resistance.
Ivermectin education
Evidence-based discussion of ivermectin as an antiparasitic medicine, including approved uses, limitations and safety concerns.
Emerging infections
Vaccines, respiratory viruses, COVID-19, outbreak response and interpretation of evolving evidence.
Medical training
Doctor of Medicine
Harvard Medical School
Internal medicine residency
Brigham and Women’s Hospital
Infectious diseases fellowship
Massachusetts General Hospital
Professor of Medicine
Harvard Medical School
Selected professional focus
- ✓Clinical trials of antiretroviral therapies
- ✓Safety and toxicity of HIV medicines
- ✓Cost-effectiveness of HIV-management strategies
- ✓Clinical education in infectious diseases
- ✓Interpretation of emerging-infection and vaccine evidence
Professional contribution
Selected roles and contributions
- ✓Editor-in-Chief of Clinical Infectious Diseases
- ✓Clinical Director, Division of Infectious Diseases, Brigham and Women’s Hospital
- ✓Leader of the Brigham HIV Program
- ✓Co-director of the Mass General Brigham Infectious Diseases Fellowship Program
- ✓Author of nearly 1,000 HIV and ID Observations posts between 2008 and 2026
Professional and medicine sources
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Profile review & publication
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Medical information notice: This profile and related articles provide general educational information and do not replace diagnosis, treatment or advice from a licensed healthcare professional. Azithromycin should be used only for appropriate bacterial indications. Antibiotics do not treat viral infections. Ivermectin is not an antibiotic, and the FDA has not authorized or approved it for prevention or treatment of COVID-19.



