PE Paul E. Sax, MD
PublishedJuly 20, 2026
Last reviewedAugust 23, 2026
Medical Expert Profile

Paul E. Sax, MD

Infectious Diseases Physician · Professor of Medicine · HIV Specialist

Paul E. Sax, MD, is Clinical Director of the Division of Infectious Diseases at Brigham and Women’s Hospital and Professor of Medicine at Harvard Medical School. He is internationally recognized for HIV clinical care, infectious-disease education, clinical research and clear communication of complex medical evidence.

Doctor of Medicine Harvard Medical School Editor-in-Chief, Clinical Infectious Diseases
Professional overview

About Dr. Sax

His career combines infectious-disease clinical leadership, HIV medicine,
medical education, editorial work and research involving antiretroviral therapy.

Clinical and academic leadership

Dr. Sax serves as Clinical Director of the Division of Infectious Diseases at
Brigham and Women’s Hospital, holds the Bruce A. Beal and Robert L. Beal
Distinguished Chair in Infectious Diseases and is Professor of Medicine at Harvard Medical School.

Editorial and educational contribution

He is Editor-in-Chief of Clinical Infectious Diseases, a Section Editor for
the HIV/AIDS section of UpToDate and a long-standing writer and educator
on HIV, antibiotics, emerging infections and clinical practice.

Clinical and educational areas

Areas of expertise

ClearMed Journal presents medicines by their generic ingredient names and separates
antibiotics, antiparasitic medicines and antiviral therapies accurately.

Infectious diseases

Clinical evaluation, treatment decisions, prevention and communication across a broad range of infections.

HIV medicine

Antiretroviral therapy, treatment safety, drug toxicity, prevention and long-term HIV care.

Azithromycin

Educational context for azithromycin, a macrolide antibacterial medicine used for selected susceptible bacterial infections.

Antibiotic stewardship

Selecting antibiotics only when clinically indicated, limiting unnecessary exposure and reducing resistance.

Ivermectin education

Evidence-based discussion of ivermectin as an antiparasitic medicine, including approved uses, limitations and safety concerns.

Emerging infections

Vaccines, respiratory viruses, COVID-19, outbreak response and interpretation of evolving evidence.

Education and professional development

Medical training

MD

Doctor of Medicine

Harvard Medical School

RES

Internal medicine residency

Brigham and Women’s Hospital

FEL

Infectious diseases fellowship

Massachusetts General Hospital

HMS

Professor of Medicine

Harvard Medical School

Selected professional focus

  • Clinical trials of antiretroviral therapies
  • Safety and toxicity of HIV medicines
  • Cost-effectiveness of HIV-management strategies
  • Clinical education in infectious diseases
  • Interpretation of emerging-infection and vaccine evidence
Leadership and communication

Professional contribution

Selected roles and contributions

  • Editor-in-Chief of Clinical Infectious Diseases
  • Clinical Director, Division of Infectious Diseases, Brigham and Women’s Hospital
  • Leader of the Brigham HIV Program
  • Co-director of the Mass General Brigham Infectious Diseases Fellowship Program
  • Author of nearly 1,000 HIV and ID Observations posts between 2008 and 2026
ClearMed Journal standards

Profile review & publication

Profile information reviewed and published by ClearMed Journal

Professional titles, training, expertise, roles and linked records are presented using the profile information and professional sources maintained for this expert.

Published: July 20, 2026Last reviewed: August 23, 2026Editorial status: Published
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Medical information notice: This profile and related articles provide general educational information and do not replace diagnosis, treatment or advice from a licensed healthcare professional. Azithromycin should be used only for appropriate bacterial indications. Antibiotics do not treat viral infections. Ivermectin is not an antibiotic, and the FDA has not authorized or approved it for prevention or treatment of COVID-19.